As far as TSA is concerned, no. As long as the first and last name match her ID, she will be fine. The only way this might cause as issue is if the traveler has TSA PreCheck. Generally, the name on the ticket has to match the name in the PreCheck system. If she does not have PreCheck, this is irrelevant, and if she does, it can likely be corrected by the gate agent the date of travel.
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