My biggest help with taking my kids on a flight is to have the toddler on my back in a ergobaby backpack. She is contained and contented, and I have both hands free. My 5yo pulled her own suitcase last flight (when she was 4) and I have a "mommy bag" with a long strap so that I can hang it across me, messenger-style. Baby and bag contained and still one hand to pull a suitcase and another to hold the other kid's hand.
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